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	<title>PharmaFeed &#187; Deborah Dunsire</title>
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		<title>Millennium strikes $365M deal for Seattle Genetics&#8217; cancer antibody</title>
		<link>http://www.pharmafeed.com/millennium-strikes-365m-deal-for-seattle-genetics-cancer-antibody</link>
		<comments>http://www.pharmafeed.com/millennium-strikes-365m-deal-for-seattle-genetics-cancer-antibody#comments</comments>
		<pubDate>Wed, 16 Dec 2009 11:06:21 +0000</pubDate>
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				<category><![CDATA[M&A]]></category>
		<category><![CDATA[Deborah Dunsire]]></category>
		<category><![CDATA[Hodgkin's disease]]></category>
		<category><![CDATA[Millennium]]></category>
		<category><![CDATA[Roche]]></category>
		<category><![CDATA[Seattle Genetics]]></category>
		<category><![CDATA[Takeda]]></category>

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		<description><![CDATA[Just a few days after Seattle Genetics bid goodbye to Roche as the pharma giant pulled out of an $860 million partnership deal, the developer pulled the wraps off a new development pact with Takeda&#8217;s U.S. cancer subsidiary Millennium. Seattle Genetics gets $60 million upfront, development funds and a schedule of milestones that could total more than $230 [...]]]></description>
			<content:encoded><![CDATA[<p style="text-align: justify;">Just a few days after Seattle Genetics bid goodbye to Roche as the pharma giant pulled out of an $860 million partnership deal, the developer pulled the wraps off a new development pact with Takeda&#8217;s U.S. cancer subsidiary Millennium. Seattle Genetics gets $60 million upfront, development funds and a schedule of milestones that could total more than $230 million from Millennium as they team up on a promising &#8221;empowered antibody&#8221; now in a pivotal trial for Hodgkin&#8217;s disease and lymphomas.</p>
<p style="text-align: justify;">[ad]</p>
<p style="text-align: justify;">The Seattle-based developer put this program&#8211;brentuximab vedotin&#8211;in the spotlight at the 2008 summer ASCO meeting. At that point, researchers stirred considerable interest in the antibody, with early-stage data demonstrating that it had either eradicated or was able to shrink tumors in 12 of 38 patients in a clinical trial. And as Xconomy notes, follow-up data on the program underscored its potential. Pivotal Phase II data is due in the second half of 2010 with marketing applications expected for the U.S. and Europe in 2011.</p>
<p style="text-align: justify;">The Takeda Group snared commercial rights to the drug outside of the U.S. and Canada, where Seattle Genetics retains full rights. And Takeda also says that it expects to provide $75 million in development funding over the next three years.</p>
<p style="text-align: justify;">&#8220;This collaboration closely aligns with our growth strategy, which includes both internal and external opportunities,&#8221; said Millennium CEO Deborah Dunsire. &#8220;We are very excited to bring forward a novel medicine which will help us increase our reach in oncology throughout Europe and the rest of the world.&#8221;</p>
<p style="text-align: justify;">Source: FierceBiotech</p>
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